{"id":4464,"date":"2019-07-10T04:08:31","date_gmt":"2019-07-10T04:08:31","guid":{"rendered":"https:\/\/www.echelecabeza.com\/?p=4464"},"modified":"2025-01-10T12:23:13","modified_gmt":"2025-01-10T12:23:13","slug":"ghb","status":"publish","type":"post","link":"https:\/\/www.echelecabeza.com\/ghb\/","title":{"rendered":"GHB"},"content":{"rendered":"<p>El \u00e1cido gammahidroxibutirico conocido tambi\u00e9n como \u00e9xtasis liquido, es un depresor del SNC (Sistema Nervioso Central) que se presenta generalmente en forma l\u00edquida, incoloro, indoloro y ocasionalmente salado, es utilizado para el tratamiento de la narcolepsia y alcoholismo, adem\u00e1s de ser usado por algunas personas para estimular la hormona del crecimiento. Referente a su estado socio legal, el GHB es una droga de clase C, lo que significa que es ilegal.<\/p>\n<p><strong>Mecanismo de acci\u00f3n<\/strong><\/p>\n<p>Existe considerable evidencia de que el GHB puede ser un neuromodulador en el cerebro, dicha sustancia tiene m\u00faltiples mecanismos neuronales, sin embargo, su principal acci\u00f3n se centra en la activaci\u00f3n de ambos receptores de los \u00e1cidos gamma-aminobuturicos de tipo B (GABA(B)), y un receptor GHB especifico. Esta interacci\u00f3n compleja (GHB-GABA(B)) es probablemente el responsable de los efectos qu\u00edmicos, el\u00e9ctricos, toxicol\u00f3gicos y comportamentales de la sustancia.<\/p>\n<p><strong>Efectos<\/strong><\/p>\n<p>Los efectos del GHB se asemejan a los del alcohol, sus principales efectos son:<br \/>\n-Relajaci\u00f3n<\/p>\n<p>-Sensaciones de bienestar<\/p>\n<p>-Perdida de la inhibici\u00f3n<\/p>\n<p>-Aumento de la actividad sexual<\/p>\n<p>-Inductor del sue\u00f1o<\/p>\n<p>El GHB tiene alto riesgo y reporte de casos de sobredosificaciones.<\/p>\n<p><strong>Efectos secundarios<\/strong><\/p>\n<p><strong>mareos, n\u00e1useas, v\u00f3mitos, visi\u00f3n borrosa o doble, descoordinaci\u00f3n y somnolencia<\/strong><\/p>\n<p>en algunas personas y dependiendo la dosificaci\u00f3n dentro de la sesi\u00f3n del consumo puede aparecer cefaleas, contracciones musculares, diarrea, amnesias, convulsiones, estados profundos de inconciencia.<\/p>\n<p><strong>Recomendaciones<\/strong><\/p>\n<p>La dosificaci\u00f3n del GHB puede variar:<\/p>\n<ul>\n<li>0.5 ml a 1 ml es una dosis com\u00fan de inicio<\/li>\n<li>0.1 a 1.5 ml genera los efectos esperados con intensidad normal<\/li>\n<li>0.5 a 2 ml dosis elevadas<\/li>\n<li>0.5 a 3 ml aumenta el riesgo de generar inconciencia, coma o la muerte<\/li>\n<\/ul>\n<p><strong>&#8211;<\/strong>Evitar la mezcla con alcohol, opioides, benzodiacepinas, y otros depresores del SNC, puede aumentar f\u00e1cilmente el riesgo de sobredosificaciones o intoxicaciones<\/p>\n<p>-Evitar el consumo con condiciones m\u00e9dicas respiratorias<\/p>\n<p>-Si se considera re-dosificar se recomienda esperar al menos 2 a 3 horas<\/p>\n<p>-Evitar el consumo si se esta bajo tratamiento de VIH, algunos retrovirales pueden tener una interacci\u00f3n adversa con la sustancia<\/p>\n<p>-Evitar el consumo bajo estado de embarazo o lactancia[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>El \u00e1cido gammahidroxibutirico conocido tambi\u00e9n como \u00e9xtasis liquido, es un depresor del SNC que se presenta generalmente en forma l\u00edquida, incoloro, indoloro y ocasionalmente salado, es utilizado para el tratamiento de la narcolepsia y alcoholismo, adem\u00e1s de ser usado por algunas personas para estimular la hormona del crecimiento. 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